*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV7800000
CHEMICAL NAME           : 4-Pyrimidinecarboxylic acid,
                          1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-
CAS REGISTRY NUMBER     : 703-95-7
LAST UPDATED            : 198605
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H3-F-N2-O4
MOLECULAR WEIGHT        : 174.10
WISWESSER LINE NOTATION : T6VMVMJ EVQ FF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * ENT-26398
   * 5-Fluoroorotate
   * Fluoroorotic acid
   * 5-Fluoroorotic acid
   * FO
   * FOA
   * NSC 31712
   * Orotic acid, 5-fluoro-
   * 4-Pyrimidinecarboxylic acid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-
   * Ro 2-9945
   * 1,2,3,6-Tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ADTEAS Advances in Teratology.  (New York, NY)  V.1-5, 1966-72.
   Discontinued.  Volume(issue)/page/year: 3,181,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 981 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York,
   Springer, 1975  Volume(issue)/page/year: -,49,1975

 
                            *** END OF RECORD ***