*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV7704200
CHEMICAL NAME           : 5-Pyrimidinecarboxamide,
                          2-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-
CAS REGISTRY NUMBER     : 72412-36-3
LAST UPDATED            : 198303
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H21-N5-O2
MOLECULAR WEIGHT        : 279.39
WISWESSER LINE NOTATION : T6N CNJ BZ DO1 EVM1- BT5NTJ A2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methyl-5-pyrimidinecarboxam
     ide
   * 2-(2-Amino-4-methoxy-5-pyrimidinyl carboxamidomethyl)-1-ethylpyrrolidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,437,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,437,1982
 
                            *** END OF RECORD ***