*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6320000
CHEMICAL NAME           : Pyrimidine,
                          6-(allyloxy)-2-(methylamino)-4-(4-methyl-1-piperaziny
                          l)-5-(methylthio)-, monohydrochloride
CAS REGISTRY NUMBER     : 55477-42-4
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H23-N5-O-S.Cl-H
MOLECULAR WEIGHT        : 345.94
WISWESSER LINE NOTATION : T6N DNTJ A1 D- DT6N CNJ BM1 ES1 FO2U1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   6-(Allyloxy)-2-(methylamino)-4-(4-methyl-1-piperazinyl)-5-(methylthio)py
     rimidine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
                            *** END OF RECORD ***