*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV0725000
CHEMICAL NAME           : 1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-6-methoxy-
CAS REGISTRY NUMBER     : 20315-68-8
BEILSTEIN REFERENCE NO. : 0172873
REFERENCE               : 5-23-12-00047 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H14-N2-O
MOLECULAR WEIGHT        : 202.28
WISWESSER LINE NOTATION : T B656 EM HMT&&J LO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-MeOthbc
   * 6-Methoxytetrahydro-beta-carboline
   * 6-Methoxy-1,2,3,4-tetrahydro-beta-carboline
   * 6-Methoxytryptoline
   * 2,3,4,9-Tetrahydro-6-methoxy-1H-pyrido(3,4-b)indole
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 415 mg/kg/5W-C
TOXIC EFFECTS :
   Endocrine - changes in pituitary weight
   Related to Chronic Data - changes in ovarian weight
   Related to Chronic Data - changes in uterine weight
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,47,1978
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 440 mg/kg/5W-I
TOXIC EFFECTS :
   Vascular - regional or general arteriolar constriction
   Endocrine - changes in spleen weight
   Related to Chronic Data - changes in uterine weight
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,47,1978
 
                            *** END OF RECORD ***