*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6260900
CHEMICAL NAME           : 2-Pyrimidinamine,
                          5,5'-methylenebis(N-(1-(1,3-benzodioxol-5-ylmethyl)-4
                          -piperidinyl)-N-methy l-
CAS REGISTRY NUMBER     : 76167-84-5
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C37-H44-N8-O4
MOLECULAR WEIGHT        : 664.89
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5,5'-Methylenebis(N-(1-(1,3-benzodioxol-5-ylmethyl)-4-piperidinyl)-N-met
     hyl-2-pyrimidinamine)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,951,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,951,1980
 
                            *** END OF RECORD ***