*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6260356
CHEMICAL NAME           : 2-Pyrimidinamine,
                          4-chloro-6-(4-methyl-1-piperazinyl)-5-(methylthio)-N-
                          (phenylmethyl)-
CAS REGISTRY NUMBER     : 59717-63-4
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H22-Cl-N5-S
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Benzylamino-4-N-methylpiperazino-5-methylthio-6-chloropyrimidine
   *   4-Chloro-6-(4-methyl-1-piperazinyl)-5-(methylthio)-N-(phenylmethyl)-2-py
     rimidinamine
   * UK 177
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4166852
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 85 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4166852
 
                            *** END OF RECORD ***