*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6233927
CHEMICAL NAME           : 2-Pyrimidinamine,
                          4,6-bis(1-methyl-4-piperidinyl)oxy)-N-methyl-5-(methy
                          lthio)-N-(3- (trifluoromethyl)phenyl)-, hydrobromide,
                          hydrate (2:4:1)
CAS REGISTRY NUMBER     : 57259-15-1
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H34-F3-N5-O2-S.2Br-H.1/2H2-O
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 87 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
                            *** END OF RECORD ***