*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6232856
CHEMICAL NAME           : 2-Pyrimidinamine,
                          4,6-bis(1-methyl-4-piperidinyl)oxy)-N-(3,4-dimethoxyp
                          henyl)-N-methyl-5- (methylthio)-
CAS REGISTRY NUMBER     : 57304-25-3
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H39-N5-O4-S
MOLECULAR WEIGHT        : 517.76
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (3',4'-Dimethoxy)-2-N-methylanilino-4,6-di((4')-N-methylpiperidyl)-oxy-5
     -methylthiopyrimidin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 65 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
                            *** END OF RECORD ***