*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV1164450
CHEMICAL NAME           : Pyrido(2,3-d)pyrimidin-4(3H)-one,
                          2-methyl-3-(1-piperidinylmethyl)-
CAS REGISTRY NUMBER     : 101204-88-0
LAST UPDATED            : 198812
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-N4-O
MOLECULAR WEIGHT        : 258.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * LK 42/82
   * 2-Methyl-3-(piperidinomethyl)pyrido(2,3-d)pyrimidin-4(3H)-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 44,572,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   37,541,1985
 
                            *** END OF RECORD ***