*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV1152490
CHEMICAL NAME           : 4H-Pyrido(1,2-a)pyrimidine-3-acetic acid,
                          9-((4-acetyl-3-hydroxy-2-propylphenoxy)
                          methyl)-4-oxo-
CAS REGISTRY NUMBER     : 112668-63-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C22-H22-N2-O6
MOLECULAR WEIGHT        : 410.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (9-(4-Acetyl-3-hydroxy-2-n-propylphenoxymethyl)-4-oxo-pyrido(1,2-a)pyrim
     idin-3-yl)acetic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4798832
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4798832
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4798832
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4798832
 
                            *** END OF RECORD ***