*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV1146000
CHEMICAL NAME           : 2(1H)-Pyridone, 1-(m-aminophenyl)-
CAS REGISTRY NUMBER     : 134-37-2
BEILSTEIN REFERENCE NO. : 1526918
REFERENCE               : 5-21-07-00122 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H10-N2-O
MOLECULAR WEIGHT        : 186.23
WISWESSER LINE NOTATION : T6NVJ AR CZ
SYNONYMS/TRADE NAMES :
   * 1-(m-Aminofenylo)-2-pirydonu
   * Aminophenylpyridone
   * 1-m-Aminophenyl-2-pyridone
   * 1-(3-Aminophenyl)-2-(1H)-pyridinone
   * 1-(3-Aminophenyl)-2-pyridone
   * Amphenidone
   * Dornwal
   * Dornwall
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2300 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 19,390,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 19,390,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 20,155,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 565 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 20,155,1963
 
                            *** END OF RECORD ***