*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU9990700
CHEMICAL NAME           : 5H-Pyrido(4,3-b)indole,
                          1,2,3,4,4a,9b-hexahydro-2,6,8-trimethyl-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 40431-55-8
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H20-N2.2Cl-H
MOLECULAR WEIGHT        : 289.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,2,3,4,4a,9b-Hexahydro-2,6,8-trimethyl-5H-pyrido(4,3-b)indole  
   dihydrochloride
   * 2,6,8-Trimethyl-1,2,3,4,4a,9b-hexahydro-gamma-carboline, dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antipsychotic
   Behavioral - analgesia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 6,512,1972
 
                            *** END OF RECORD ***