*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU9782000
CHEMICAL NAME           : 5H-Pyrido(4,3-b)indole-8-carboxylic acid,
                          1,2,3,4-tetrahydro-2-methyl-, ethyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 36911-68-9
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H18-N2-O2.Cl-H
MOLECULAR WEIGHT        : 294.81
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-(Ethoxycarbonyl)-2-methyl-1,2,3,4-tetrahydro-gamma-carboline  
   hydrochloride
   * 1,2,3,4-Tetrahydro-2-methyl-5H-pyrido(4,3-b)indole-8-carboxylic acid  
   ethyl ester HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 520 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antipsychotic
   Behavioral - analgesia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 6,512,1972
 
                            *** END OF RECORD ***