*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU8820000
CHEMICAL NAME           : 6H-Pyrido(4,3-b)carbazole,
                          1-((3-(4-aminopropyl-1-piperazinyl)propyl)amino)-9-me
                          thoxy-5- methyl-
CAS REGISTRY NUMBER     : 74861-79-3
BEILSTEIN REFERENCE NO. : 5661405
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C27-H36-N6-O
MOLECULAR WEIGHT        : 460.69
WISWESSER LINE NOTATION : T D6 B656 FN LMJ J1 PO1 EM3- AT6N DNTJ D3Z
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,1212,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,1212,1980
 
                            *** END OF RECORD ***