*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU8815000
CHEMICAL NAME           : 10H-Pyrido(3,2-b)(1,4)benzothiazine,
                          10-(3-(1-pyrrolidinyl)propyl)-
CAS REGISTRY NUMBER     : 67466-11-9
BEILSTEIN REFERENCE NO. : 0292781
REFERENCE               : 4-27-00-07168 (Beilstein Handbook Reference)
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H21-N3-S
MOLECULAR WEIGHT        : 311.48
WISWESSER LINE NOTATION : T C666 BN DN ISJ B3- AT5NTJ
SYNONYMS/TRADE NAMES :
   * D 218
   * 10-(3-(1-Pyrrolidinyl)propyl)-10H-pyrido(3,2-b)(1,4)benzothiazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 312 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,489,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 104 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,489,1958
 
                            *** END OF RECORD ***