*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU4015590
CHEMICAL NAME           : Pyridinium,
                          3-(1,1-dimethylpyrrolidinium-2-yl)-1-methyl-,
                          diiodide
CAS REGISTRY NUMBER     : 5468-47-3
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H20-N2.2I
MOLECULAR WEIGHT        : 446.14
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Di-iodure de dimethylnicotinium
   * N,N-Dimethylnicotinium diiodide
   * 3-(1,1-Dimethylpyrrolidinium-2-yl)-1-methylpyridinium diiodide
   * beta-(N-Methylpyrrolidine)pyridine di-iodomethylate
   * Nicotine dimethiodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1009 mg/kg
TOXIC EFFECTS :
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,586,1948
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 288 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   21,553,1958
 
                            *** END OF RECORD ***