*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UT6386500
CHEMICAL NAME           : Pyridine, 4-nitrosomethylamino-
CAS REGISTRY NUMBER     : 16219-99-1
BEILSTEIN REFERENCE NO. : 0472145
REFERENCE               : 5-22-14-00724 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H7-N3-O
MOLECULAR WEIGHT        : 137.16
WISWESSER LINE NOTATION : T6NJ DN1&NO
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * N-Methyl-N-nitroso-4-aminopyridine
   * N-Nitroso-N-methyl-4-aminopyridine
   * 4-Nitrosomethylaminopyridine
   * Pyridine, 4-(methylnitrosamino)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Gastrointestinal - ulceration or bleeding from stomach
   Gastrointestinal - changes in structure or function of esophagus
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 62,153,1979
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 mmol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 3,415,1982
 
                            *** END OF RECORD ***