*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UT6305000
CHEMICAL NAME           : Pyridine, 4-(2-(1-naphthyl)vinyl)-, hydrochloride
CAS REGISTRY NUMBER     : 25796-01-4
LAST UPDATED            : 199206
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C17-H13-N.Cl-H
MOLECULAR WEIGHT        : 267.77
WISWESSER LINE NOTATION : L66J B1U1- DT6NJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(2-(1-Naphthalenyl)ethenyl)pyridine hydrochloride
   * 4-(1-Naphthylvinyl)-pyridine hydrochloride
   * 4-(2-(1-Naphthyl)vinyl)pyridine hydrochloride
   * NVP
   * Pyridine, 4-(2-(1-naphthalenyl)ethenyl)-, hydrochloride
   * YuB-25
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   11,187,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   11,187,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   11,187,1970
 
                            *** END OF RECORD ***