*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US6427100
CHEMICAL NAME           : 3,5-Pyridinedicarboxylic acid,
                          1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(4-(4-
                          (diphenylmethyl)-1-piperazinyl)phenyl)ethyl methyl
                          ester, dihydrochloride, (R)-(-)-
CAS REGISTRY NUMBER     : 189624-86-0
LAST UPDATED            : 199806
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C41-H42-N4-O6.2Cl-H
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (R)-AE0047
   * (R)-(-)-AE 0047
   * (R)-(-)-Watanidipine hydrochloride
   * Watanidipine hydrochloride (R)-enantiomer
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 25(Suppl 3),S745,1997
 
                            *** END OF RECORD ***