*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US7969400
CHEMICAL NAME           : 3,5-Pyridinedicarboxylic acid,
                          1,4-dihydro-4-(4-(difluoromethoxy)phenyl)-2,6-dimethy
                          l-, diethyl ester
CAS REGISTRY NUMBER     : 84761-72-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H23-F2-N-O5
MOLECULAR WEIGHT        : 395.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2,6-Dimethyl-3,5-diethoxycarbonyl-4-(p-difluoromethoxyphenyl)-1,4-dihydr
     opyridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 16,817,1982
 
                            *** END OF RECORD ***