*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US7968332
CHEMICAL NAME           : 3,5-Pyridinedicarboxylic acid,
                          1,4-dihydro-2-amino-6-methyl-4-(3-nitrophenyl)-,
                          3-(1-(diphenylmethyl)-3-azetidinyl)-5-(1-methylethyl)
                          esster, (+-)-
CAS REGISTRY NUMBER     : 123524-52-7
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C33-H34-N4-O6
MOLECULAR WEIGHT        : 582.71
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Azelnidipine
   * CS 905
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3640 mg/kg/1Y-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Nutritional and Gross Metabolic - changes in chlorine
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 25,1757,1997
 
                            *** END OF RECORD ***