*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US5700000
CHEMICAL NAME           : 3-Pyridinecarboxylic acid,
                          2-((4-ethoxyphenyl)amino)-, 2-(dimethylamino)ethyl
                          ester, monohydrochloride
CAS REGISTRY NUMBER     : 75449-73-9
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H23-N3-O3.Cl-H
MOLECULAR WEIGHT        : 365.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-((4-Ethoxyphenyl)amino)-3-pyridinecarboxylic acid  
   2-(dimethylamino)ethyl ester HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 36,657,1979
 
                            *** END OF RECORD ***