*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US4551100
CHEMICAL NAME           : 2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro-,
                          hydrochloride
CAS REGISTRY NUMBER     : 103878-83-7
LAST UPDATED            : 199509
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H10-Cl-N3-O.Cl-H
MOLECULAR WEIGHT        : 236.12
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Lazabemide
   * Ro 19-6327
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 30 gm/kg
SEX/DURATION            : male 9 week(s) pre-mating
                          female 2 week(s) pre-mating  - 3 week(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 22(suppl 11),S2785,199
 
                            *** END OF RECORD ***