*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR9281000
CHEMICAL NAME           : 3-Pyridineacrylic acid, 2-(1-piperazinyl)ethyl ester,
                          trihydrochloride
CAS REGISTRY NUMBER     : 4415-53-6
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H19-N3-O2.3Cl-H
MOLECULAR WEIGHT        : 370.74
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Propenoic acid, 3-(3-pyridinyl)-, 2-(1-piperazinyl)ethyl ester,  
   trihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 199 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - analgesia
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 55,290,1966
 
                            *** END OF RECORD ***