*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR9277000
CHEMICAL NAME           : 3-Pyridineacrylic acid,
                          2-(4-(p-methoxyphenyl)-1-piperazinyl)ethyl ester
CAS REGISTRY NUMBER     : 4480-22-2
BEILSTEIN REFERENCE NO. : 0576092
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H25-N3-O3
MOLECULAR WEIGHT        : 367.49
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Piperazineethanol, 4-(p-methoxyphenyl)-, 3-pyridineacrylate (ester)
   * 2-Propenoic acid, 3-(3-pyridinyl)-,  
   2-(4-(4-methoxyphenyl)-1-piperazinyl)ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
   Behavioral - analgesia
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 55,290,1966
 
                            *** END OF RECORD ***