*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR6135300
CHEMICAL NAME           : 3(2H)-Pyridazinone,
                          6-(4-amino-3,5-dimethyl-1H-pyrazol-1-yl)-, hydrazone,
                          dihydrochloride
CAS REGISTRY NUMBER     : 70589-21-8
LAST UPDATED            : 199703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H13-N7.2Cl-H
MOLECULAR WEIGHT        : 292.21
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-(4-Amino-3,5-dimethyl-1H-pyrazol-1-yl)-3(2H)-pyridazinone hydrazone  
   dihydrochloride
   * 3-Hydrazino-6-(3,5-dimethyl-4-amino-1-pyrazolyl)pyridazine  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 14,439,1979
 
                            *** END OF RECORD ***