*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR0809305
CHEMICAL NAME           : Pyrazolo(3,4-d)thiazolo(3,2-a)pyrimidin-4(1H)-one,
                          6-(4-fluorophenyl)-
CAS REGISTRY NUMBER     : 152423-11-5
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H17-F-N4-O-S
MOLECULAR WEIGHT        : 296.40
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-(4-Fluorophenyl)pyrazolo(3,4-d)thiazolo(3,2-a)pyrimidin-4(1H)-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 28,363,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 28,363,1993
 
                            *** END OF RECORD ***