*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ9890000
CHEMICAL NAME           : 1H-Pyrazolo(3,4-b)(1,4)benzoxazepine,
                          4,5-dihydro-1,3-dimethyl-4-(2-propynyl)-
CAS REGISTRY NUMBER     : 22086-98-2
BEILSTEIN REFERENCE NO. : 0544179
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H15-N3-O
MOLECULAR WEIGHT        : 253.33
WISWESSER LINE NOTATION : T C576 BO DNN HN IHJ D1 F1 H2UU1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4,5-Dihydro-1,3-dimethyl-4-(2-propynyl)-1H-pyrazolo(3,4-b)(1,4)benzoxaze
     pine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 980 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Nutritional and Gross Metabolic - body temperature decrease
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,42,1972
 
                            *** END OF RECORD ***