*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ9834000
CHEMICAL NAME           : 1H-Pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione,
                          5-(dimethylamino)-8-hydroxy-9-methyl- 2-propyl-
CAS REGISTRY NUMBER     : 35306-78-6
BEILSTEIN REFERENCE NO. : 0626010
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H20-N4-O3
MOLECULAR WEIGHT        : 316.40
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-Dimethylamino-6-hydroxy-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2
     ,4-benzotriazine
   * 6-HA
   * 6-Hydroxyazapropazone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
   Skin and Appendages - hair
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,666,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
   Skin and Appendages - hair
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,666,1973
 
                            *** END OF RECORD ***