*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ7889000
CHEMICAL NAME           : 1H-Pyrazole-1-pentanamide,
                          3-((imino((2,2,2-trifluoroethyl)amino)methyl)amino)-
CAS REGISTRY NUMBER     : 84545-30-2
LAST UPDATED            : 199507
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H17-F3-N6-O
MOLECULAR WEIGHT        : 306.34
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * ICI 162846
   *   3-((Imino((2,2,2-trifluoroethyl)amino)methyl)amino)-1H-pyrazole-1-pentan
     amide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 365 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 15,366,1987
 
                            *** END OF RECORD ***