*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ6104000
CHEMICAL NAME           : Pyrazole, 3-amino-4-phenyl-
CAS REGISTRY NUMBER     : 5591-70-8
BEILSTEIN REFERENCE NO. : 0742774
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H9-N3
MOLECULAR WEIGHT        : 159.21
WISWESSER LINE NOTATION : T5MNJ CZ DR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-Amino-4-phenyl pyrazole
   * 1H-Pyrazol-4-amine, 4-phenyl-
   * Pyrazole, 3(or 5)-amino-4-phenyl-
   * SKF 1572
   * USAF EL-34
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,259,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
                            *** END OF RECORD ***