*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ6393750
CHEMICAL NAME           : Pyrazole-4-carboxylic acid,
                          5-(3,4-dihydro-2-methyl-4-oxoquinazolin-3-yl)-1-pheny
                          l-, ethyl ester
CAS REGISTRY NUMBER     : 104907-90-6
BEILSTEIN REFERENCE NO. : 5458015
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H18-N4-O3
MOLECULAR WEIGHT        : 374.43
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5-(3,4-Dihydro-2-methyl-4-oxoquinazolin-3-yl)-1-phenylpyrazole-4-carboxy
     lic acid ethyl ester
   * 1H-Pyrazole-4-carboxylic acid,  
   5-(2-methyl-4-oxo-3(4H)-quinazolinyl)-1-phenyl-, ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 21,291,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 21,291,1986
 
                            *** END OF RECORD ***