*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ6300000
CHEMICAL NAME           : 1H-Pyrazole-3-carboxamide,
                          1-(3-chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-
CAS REGISTRY NUMBER     : 54708-74-6
BEILSTEIN REFERENCE NO. : 0892483
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H14-Cl-N3-O3
MOLECULAR WEIGHT        : 295.75
WISWESSER LINE NOTATION : T5NNJ AR CG& CVM2Q EO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3-Chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-1H-pyrazole-3-carboxamide
   * PZ-249
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 680 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antipsychotic
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 25,781,1975
 
                            *** END OF RECORD ***