*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ4926074
CHEMICAL NAME           : 1H-Pyrazole-4-acetic acid,
                          1-methyl-5-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-,
                          ethyl ester
CAS REGISTRY NUMBER     : 160662-12-4
LAST UPDATED            : 199603
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H20-N4-O3
MOLECULAR WEIGHT        : 388.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ethyl  
   1-methyl-5-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-1H-pyrazole-4-acetate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 29,707,1994
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 29,707,1994
 
                            *** END OF RECORD ***