*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ4915000
CHEMICAL NAME           : 1H-Pyrazole-4-acetic acid,
                          3-(4-chlorophenyl)-1-phenyl-, calcium salt (2:1)
CAS REGISTRY NUMBER     : 75821-71-5
LAST UPDATED            : 199409
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C34-H24-Cl2-N4-O4.Ca
MOLECULAR WEIGHT        : 663.60
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Calcium 3-(4-chlorophenyl)-1-phenylpyrazole-4-acetate
   * 3-(p-Chlorophenyl)-1-phenylpyrazole-4-acetic acid calcium salt (2:1)
   * 3-(4-Chlorophenyl)-1-phenyl-1H-pyrazole-4-acetic acid calcium slat (2:1)
   * 3-(4-Clorofenil)-1-fenil-1H-pirazol-4-acetico acido, sel calcica
   * Irritren
   * Lonazolac calcium
   * Lonazolaco calcico
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 845 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,655,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 670 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,655,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   18,180,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 790 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   18,180,1982
 
                            *** END OF RECORD ***