*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ4425000
CHEMICAL NAME           : Pyrazino(1',2':1,6)pyrido(3,4-b)indole-2(1H)-butanol,
                          3,4,6,7,12,12a-hexahydro-
                          alpha-(4-fluorophenyl)-alpha-methyl-
CAS REGISTRY NUMBER     : 72593-37-4
BEILSTEIN REFERENCE NO. : 4723162
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H30-F-N3-O
MOLECULAR WEIGHT        : 407.58
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Kidney, Ureter, Bladder - urine volume increased
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 22,1224,1983
 
                            *** END OF RECORD ***