*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ2282000
CHEMICAL NAME           : Pyrazinecarboxamide, N-(morpholinomethyl)-
CAS REGISTRY NUMBER     : 952-54-5
BEILSTEIN REFERENCE NO. : 1215979
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H14-N4-O2
MOLECULAR WEIGHT        : 222.28
WISWESSER LINE NOTATION : T6N DOTJ A1MV- BT6N DNJ
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * B 2310
   * Morfazinamide
   * Morphazinamid
   * Morphazinamide
   * N-(Morpholinomethyl)pyrazinecarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 3360 mg/kg/17W-I
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), diffuse
REFERENCE :
   JOHEEC Journal of Hepathology.  (Elsevier Science, 655 Avenue of the
   Americas, New York, NY  10010)  V.1-    1985-  Volume(issue)/page/year:
   25,1001,1996
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMTRAG Chemotherapia.  (Basel, Switzerland)  V.1-12, 1960-67.  For publisher
   information, see CHTHBK.  Volume(issue)/page/year: 5,39,1962
 
                            *** END OF RECORD ***