*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ2015000
CHEMICAL NAME           : Pyrazine
CAS REGISTRY NUMBER     : 290-37-9
LAST UPDATED            : 199710
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C4-H4-N2
MOLECULAR WEIGHT        : 80.10
WISWESSER LINE NOTATION : T6N DNJ
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 1,4-Diazabenzene
   * p-Diazine
   * 1,4-Diazine
   * Paradiazine
   * Piazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2730 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PBPHAW Progress in Biochemical Pharmacology.  (S. Karger AG, Postfach
   CH-4009 Basel, Switzerland) V.1-    1965-  Volume(issue)/page/year:
   1,542,1965
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 60 gm/L
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 18,581,1980
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 2500 mg/L
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 18,581,1980

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5605
       No. of Facilities: 3 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 61 (estimated)
       No. of Female Employees: 3 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***