*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ0847000
CHEMICAL NAME           : 2H-Pyran-2-one,
                          6-(2-(4'-fluoro-3,3',5-trimethyl(1,1'-biphenyl)-2-yl)
                          ethenyl)tetrahydro- 4-hydroxy-, (4-alpha,6-beta(E))-
CAS REGISTRY NUMBER     : 103064-20-6
LAST UPDATED            : 199403
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H23-F-O3
MOLECULAR WEIGHT        : 354.45
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * L 645164
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 196 mg/kg/14W-I
TOXIC EFFECTS :
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   16,320,1991
 
                            *** END OF RECORD ***