*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ0363000
CHEMICAL NAME           : Pyrano(3,4-b)indole-1-acetic acid,
                          1,3,4,9-tetrahydro-1,8-diethyl-7-hydroxy-
CAS REGISTRY NUMBER     : 101901-07-9
BEILSTEIN REFERENCE NO. : 5111552
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H21-N-O4
MOLECULAR WEIGHT        : 303.39
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1,8-Diethyl-7-hydroxy-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
   * 1,8-Diethyl-1,3,4,9-tetrahydro-7-hydroxypyrano (3,4-b)indole-1-acetic  
   acid
   * RAK 902
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1391 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 40,737,1990
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 mg/plate
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 40,747,1990
 
                            *** END OF RECORD ***