*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UO8445700
CHEMICAL NAME           : 1H-Purine-2,6-dione,
                          2,3,6,7-tetrahydro-1,3-dimethyl-8-phenyl-
CAS REGISTRY NUMBER     : 961-45-5
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H12-N4-O2
MOLECULAR WEIGHT        : 256.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Dimethyl-8-phenylxanthine
   * 8-Phenyltheophylline
   * 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-phenyl-
   * Theophylline, 8-phenyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 43,152,1954
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #5032593
 
                            *** END OF RECORD ***