*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UO8437000
CHEMICAL NAME           : 1H-Purine-2,6-dione,
                          3,7-dihydro-8-(4-(2-hydroxyethyl)-1-piperazinyl)-1,3-
                          dimethyl-
CAS REGISTRY NUMBER     : 40171-75-3
BEILSTEIN REFERENCE NO. : 1161605
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H20-N6-O3
MOLECULAR WEIGHT        : 308.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N(sup 1)-(8-Teofillina)-N(sup 4)-beta-idrossietilpiperazina
   * N(sup 1)-(Theophyllinyl-8)-N(sup 4)-beta-hydroxyethylpiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1675 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 29,802,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 29,802,1974
 
                            *** END OF RECORD ***