*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UO8430000
CHEMICAL NAME           : 1H-Purine-2,6-dione,
                          3,7-dihydro-1,3-dimethyl-7-(2-(sulfooxy)ethyl)-,
                          compd. with 5-hydroxy-6-methyl-3,4-pyridinedimethanol
                          (1:1)
CAS REGISTRY NUMBER     : 53403-97-7
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H12-N4-O6-S.C8-H11-N-O3
MOLECULAR WEIGHT        : 473.51
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ B2OSWQ F1 H1 &T6NJ B1 CQ D1Q E1Q
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Atherophylline
   * 7-(2-Hydroxyethyl)theophylline hydrogen sulfate compd. with pyridoxol
   * Pyridofylline
   * Pyridoxol compd. wtih 7-(2-hydroxyethyl)theophylline hydrogen sulfate
   * Theophyllineethylsulfate of pyridoxine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,1268,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,1268,1989
 
                            *** END OF RECORD ***