*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BZ4800000
CHEMICAL NAME           : p-Anisic acid, hydrazide
CAS REGISTRY NUMBER     : 3290-99-1
BEILSTEIN REFERENCE NO. : 0389017
REFERENCE               : 4-10-00-00454 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H10-N2-O2
MOLECULAR WEIGHT        : 166.20
WISWESSER LINE NOTATION : ZMVR DO1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Anisic acid hydrazide
   * Anisic hydrazide
   * Anisoylhydrazine
   * p-Anisoylhydrazine
   * Benzoic acid, p-methoxy-, hydrazide
   * Hydrazine, 4-methoxybenzoyl-
   * p-Methoxybenzoic acid hydrazide
   * 4-Methoxybenzoic acid hydrazide
   * p-Methoxybenzoic hydrazide
   * 4-Methoxybenzoyl hydrazide
   * (p-Methoxybenzoyl)hydrazine
   * 4-Methoxybenzoylhydrazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 178 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00894
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 gm/kg/22W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   34ZRA9 "Proceedings of the Quadrennial Conference on Cancer, 3rd, 1965,"
   Severi, L., ed., Perugia, Italy, Univ. of Perugia, 1966
   Volume(issue)/page/year: -,869,1965
 
                            *** END OF RECORD ***