*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BY0500000
CHEMICAL NAME           : Aniline, N-ethyl-p-(phenylazo)-
CAS REGISTRY NUMBER     : 2058-67-5
BEILSTEIN REFERENCE NO. : 0747223
REFERENCE               : 4-16-00-00454 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H15-N3
MOLECULAR WEIGHT        : 225.32
WISWESSER LINE NOTATION : 2MR DNUNR
COMPOUND DESCRIPTOR     : Tumorigen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Benzenamine, N-ethyl-4-(phenylazo)-
   * EAB
   * 4-(Ethylaminoazobenzene)
   * N-Ethyl-4-aminoazobenzene
   * N-Ethyl-4-(phenylazo)benzenamine
   * N-Ethyl-p-(phenylazo)aniline
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 376 mg/kg/5W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,3411,1979
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 400 mg/kg
SEX/DURATION            : female 10-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   KAIZAN Kaibogaku Zasshi.  Journal of Anatomy.  (Nippon Kaibo Gakkai, c/o
   Tokyo Daigaku Igakubu, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan)  V.1- 1928-
    Volume(issue)/page/year: 37,179,1962
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 400 mg/kg
SEX/DURATION            : female 8-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   KAIZAN Kaibogaku Zasshi.  Journal of Anatomy.  (Nippon Kaibo Gakkai, c/o
   Tokyo Daigaku Igakubu, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan)  V.1- 1928-
    Volume(issue)/page/year: 37,179,1962
 
                            *** END OF RECORD ***