*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BV8100000
CHEMICAL NAME           : Androst-5-ene-3,17-diol, 17-methyl-, (3-beta,17-beta)
CAS REGISTRY NUMBER     : 521-10-8
LAST UPDATED            : 199206
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C20-H32-O2
MOLECULAR WEIGHT        : 304.52
WISWESSER LINE NOTATION : L E5 B666 LUTJ A1 E1 FQ F1 OQ
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
                          Human
SYNONYMS/TRADE NAMES :
   * Androdiol
   * Androst-5-ene-3-beta,17-beta-diol, 17-methyl-
   * Androtestone-M
   * Androteston-M
   * Crestabolic
   * Diolandrone
   * Diolostene
   * Esjaydiol
   * MAD
   * Madiol
   * Masdiol
   * Megabion
   * Mestenediol
   * Metandiol
   * Metandriol
   * Metendiol
   * Methanabol
   * Methandiol
   * Methandriol
   * Methandrolan
   * Methostan
   * Methylandrostendiol
   * 17-Methylandrost-5-ene-3-beta,17-beta-diol
   * Metidione
   * Metildiolo
   * Metocryst
   * Nabadial
   * Neostene
   * Neosteron
   * Neutrormone
   * Neutrosteron
   * Notandron
   * Notandron-depot
   * Protandren
   * Stenediol
   * Stenibell
   * Stenosterone
   * Testodiol
   * Troformone
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - woman
DOSE                    : 64 mg/kg
SEX/DURATION            : female 26-39 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   GEFRA2 Geburtshilfe und Frauenheilkunde.  (Georg Thieme Verlag, Postfach
   732, D-7000 Stuttgart 1, Fed. Rep. Ger.)  V.1-    1939-
   Volume(issue)/page/year: 13,216,1953
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 42 gm/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - cytological changes (including
   somatic cell genetic material)
   Reproductive - Specific Developmental Abnormalities - hepatobiliary system
REFERENCE :
   RMEMDQ Revue Roumaine de Morphologie, d'Embryologie et de Physiologie, Serie
   Morphologie et Embryologie.  (Rompresfilatelia, POB 12-201, Bucharest,
   Romania)  V.21-    1975-  Volume(issue)/page/year: 26,33,1980
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 875 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - gastrointestinal
   system
REFERENCE :
   RMEMDQ Revue Roumaine de Morphologie, d'Embryologie et de Physiologie, Serie
   Morphologie et Embryologie.  (Rompresfilatelia, POB 12-201, Bucharest,
   Romania)  V.21-    1975-  Volume(issue)/page/year: 26,303,1980
 
                            *** END OF RECORD ***