*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BV8065500
CHEMICAL NAME           : 5-alpha-Androstan-3-one,
                          2-alpha-(hydroxymethyl)-17-beta-hydroxy-
CAS REGISTRY NUMBER     : 566-52-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H32-O3
MOLECULAR WEIGHT        : 320.52
WISWESSER LINE NOTATION : L E5 B666 OVTJ A1 E1 FQ P1Q
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * 2-alpha-Hydroxymethyl-17-beta-hydroxy-5-alpha-androstan-3-one
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3360 ug/kg
SEX/DURATION            : male 21 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   ACENA7 Acta Endocrinologica (Copenhagen).  (Periodica, Skolegade 12 E,
   DK-2500 Valby, Denmark) V.1-    1948-  Volume(issue)/page/year: 49,145,1965
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 20 mg/kg
SEX/DURATION            : female 10 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
   Reproductive - Maternal Effects - other effects
REFERENCE :
   ECJPAE Endocrinologia Japonica.  (Japan Pub. Trading Co., Ltd., POB 5030,
   Tokyo International, Tokyo, Japan)  V.1-    1954-  Volume(issue)/page/year:
   23,327,1976
 
                            *** END OF RECORD ***