*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UO7440537
CHEMICAL NAME           : 9H-Purin-6-amine,
                          9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-
CAS REGISTRY NUMBER     : 110143-10-7
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H12-F-N5-O2
MOLECULAR WEIGHT        : 253.27
SYNONYMS/TRADE NAMES :
   * 9-(2,3-Dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purin-6-amine
   * F-ddA
   * 2'-beta-Fluoro-2',3'-dideoxyadenosine
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1250 mg/kg/5D-I
TOXIC EFFECTS :
   Cardiac - other changes
   Related to Chronic Data - death
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   27,167,1995
 
                            *** END OF RECORD ***