*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UK8419700
CHEMICAL NAME           : Prost-5-en-1-oic acid, 12-fluoro-9,11,15-trihydroxy-,
                          methyl ester, (+)-, (5Z,9-alpha, 11-alpha,15-alpha)-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H37-F-O5
MOLECULAR WEIGHT        : 388.58
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * (+)-12-Fluoro-13,14-dihydro-pgf2-alpha methyl ester
   * (+)-12-Fluoro-13,14-dihydroprostaglandin F2-alpha methyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 50 ug/kg
SEX/DURATION            : female 5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,839,1981
 
                            *** END OF RECORD ***