*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UK8362500
CHEMICAL NAME           : Prost-2,13-dien-1-oic acid,
                          11,15-dihydroxy-17,20-dimethyl-9-oxo-,
                          (2E,11-alpha,13E,15S,17S)-
CAS REGISTRY NUMBER     : 74397-12-9
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H36-O5
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (2E,11-alpha,13E,15S,17S)-11,15-Dihydroxy-17,20-dimethyl-9-oxoprost-2,13
     -dien-1-oic acid
   * 17S,20-Dimethyl-trans-2,3-didehydro-PGE1
   * ONO 1206
   * OP 1206
   *   9-Oxo-11-alpha,15-alpha-dihydroxy-17S,20-dimethylprosta-trans-2,trans-13
     -dienoic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2041368
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2041368
 
                            *** END OF RECORD ***